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This is the most telling comparison, because it comes from a single study (REDEFINE 1), in which all three arms were assessed in parallel and it shows the additive effect of two pathways

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Some small studies suggest that L-carnitine supplementation during calorie restriction may improve the ratio of fat loss to lean mass loss, but the effect sizes are small and not all studies agree

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SLU-PP-332 Research Areas Research shows multiple areas for further slu pp 332 investigation